Rannsóknarteymi frá Mie háskólanum í Japan hefur komist að því að snemma sebrafiskafósturvísa (fósturvísa nokkrum klukkustundum eftir frjóvgun) er óhætt að geisla með 278 nm UVC.
UVC-LED í kringum 260nm eru notaðar til dauðhreinsunar þar sem þær valda og óvirkja DNA skemmdir frá bakteríum og veirum. Flestar núverandi rannsóknir beinast að áhrifum UVC með bylgjulengdum undir 240nm (207nm, 222nm, 233nm) á að drepa nýja kransæðavír. Hins vegar eru fáar rannsóknir á eiturhrifum, öryggi og svörun lífvera við UVC geislun um 280 nm.
Therefore, this time, a total of 16 irradiation doses were set in the range of 0.5 to 60 mJ/cm² using the irradiation device developed by the research group to irradiate 278 nm UVC, and zebrafish embryos were directly irradiated.
After 3 days of irradiation, the researchers evaluated the survival rate, hatching rate, heart rate, deformity rate, etc. of zebrafish embryos. The results found that all embryos remained alive under the irradiation dose below 4.5mJ/cm². However, when the dose reached 7.5 mJ/cm², the deformity rate significantly increased to 82 percent , and the survival rate decreased to 37 percent . Embryo death was observed if the dose was increased to 10 mJ/cm² and above.
Based on the above experimental results, the researchers determined that there is a biological defense system inside the zebrafish embryo, which can resist the damage caused by UVC irradiation to the greatest extent, and the limit dose that can resist UVC irradiation is 4.5 mJ/cm².
The researchers believe that the biological defense mechanism of zebrafish against UVC-induced DNA damage is that after zebrafish embryos are treated with UVC at a dose of 4.5 mJ/cm², the p53 signaling pathway in cells is immediately and urgently activated. Arrest, DNA repair, cell division/proliferation and damaged cell death in rapid response to stress. In addition, after 3 days of recovery, p53 variability was attenuated and instead activated the STAT signaling pathway, which continued to repair damaged DNA.
Rannsóknarniðurstöður þessa efnis veita vísindalegan grunn fyrir öryggi UVC-LED sem er notað á mannslíkamann. Á sama tíma komst rannsóknarhópurinn að því að UVC hentar til sótthreinsunar á bakteríum og vírusum, þar á meðal kransæðaveiru, sem og sótthreinsun í fiskeldi.
"Experts say UV" believes that: at the application level, the sterilization experience of UVC-LED is difficult to intuitively perceive, and consumers will have concerns about safety when using it. brings confidence.
GMKJ LED tæknin tekur djúpt þátt í heilbrigðum og snjöllum ljósgjöfum, veitir markaðnum alhliða UVA UVB UVC LED, innrauða IR LED VCSEL vörur og lausnir og hefur hundruð hágæða samstarfsaðila í innlendum og erlendum markaðir til að stuðla sameiginlega að notkun ljóstækni til að skapa heilbrigt og snjallt líf. orsök.
